This is my first NodeJS production site for my mate's band Sparse. I'm really enjoying using NodeJS after so long in the constrictive Drupal framework. It's a bespoke CMS with the underlying site framework following a MVC structure, using Mongo as the primary datastore, provided by MongoHQ.com. Redis handles session management for authentication for the CMS. It's hosted on the PaaS, appfog.com making deployment a breeze, and has automated daily backups to Amazon's S3 service.
The CMS allows the band members to add up-coming gigs, album details and lyrics. Additional content is pulled and proxied from the Instagram and Vimeo apis. The front-end build is using the Twitter Bootstrap. Compass sprite is used to automate the building of my icon sprite.
Bundle-All is used to compile and compress all js and css.
This is a zero budget job, and initially low traffic, so the forementioned hosting setup is perfect. If the band goes global, it wouldn't be much trouble to deploy the project to a Amazon VPS, with memcached enabled nginx servering the pages to improve site performance further and move static assets to a CDN such as Amazon's Cloudfront.